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Clomicalm (clomipramine
hydrochloride) Information
Generic
Name: Clomipramine (klo-mip-ra-meen)
Brand
Name(s): Anafranil (Novartis), Clomicalm (Novartis)
Description:
CLOMICALM (clomipramine hydrochloride) Tablets belong to
the dibenzazepine class of tricyclic antidepressants. Clomipramine
hydrochloride is 3-chloro-5 [3-(dimethyl-amino)propyl]-10, 11-dihydro-5H-dibenz[b,f]azepine
monohydrochloride. CLOMICALM Tablets are oblong, light brown in
color and contain clomipramine hydrochloride formulated together
with meat components. CLOMICALM Tablets are available in 20, 40
and 80 mg tablet strengths in color-coded packaging for oral administration
to dogs.
Indications
and Usage:
Clomicalm tablets are to be used as part of a comprehensive behavioral
management program to treat separation anxiety in dogs greater than
6 months of age. Inappropriate barking or destructive behavior,
as well as inappropriate elimination (urination or defecation) may
be alleviated by the use of CLOMICALM Tablets in conjunction
with behavior modification.
Separation anxiety is
a complex behavior disorder displayed when the owner (or other attachment
figure) leaves the dog. The signs of separation anxiety evaluated
in controlled trials were vocalization, destructive behavior, excessive
salivation and inappropriate elimination. In the absence of the
owner or attachment figure, dogs with separation anxiety may exhibit
one or more of these clinical signs. Although the owner (attachment
figure) may inadvertently misinterpret this behavior, which only
happens in their absence, as spiteful, it is thought to be the result
of anxiety experienced by the dog. Punishment is not considered
appropriate for a dog with separation anxiety.
Proper recognition of
clinical signs, including a complete patient history and assessment
of the patient's household environment, is essential to accurately
diagnose and treat separation anxiety. The use of CLOMICALM
Tablets should not replace appropriate behavioral and environmental
management but should be used to facilitate a comprehensive behavioral
management program.
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Complete
product information from Novartis
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