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Anipryl by Pfizer is a medication used to treat endocrine(Cushing's Disease) and cognitive dysfunction("senility") abnormalities in dogs.

Anipryl

Anipryl ® is the veterinary trade name for a drug called selegiline hydrochloride, also known as L-deprenyl. It is used in humans for treatment of Parkinson's Disease, Alzheimer's Disease, and Cushing's Disease. The drug is approved by the FDA for use in dogs for treatment of Pituitary Dependent Hyperadrenocorticism (PDH) also known as Cushing's Disease and Canine Cognitive Dysfunction.

Anipryl is used to treat canine cognitive dysfunction and a type of Cushing's disease caused by a pituitary tumor. Because it belongs to a class of drugs called Monoamine Oxidase Inhibitors (MAO I's) it should not be given with antidepressants such as Prozac. Anipryl is available as 2mg, 5mg, 10mg, 15mg and 30mg tablets.

More details about Anipryl

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Anipryl Tablets For Dogs by Prizer

Anipryl is FDA approved for the treatment of Cushing’s disease in dogs caused by a pituitary tumor. It is also used to treat cognitive dysfunction. The usual starting dose for treating Cushing's disease is 0.45 mg/pound given in the morning. The dose for Canine Cognitive Dysfunction is 0.2-0.45 mg/pound. It may take up to one month or more to see improvement

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Anipryl For Dogs 30mg 30 Tablets Product Currently Unavailable

 

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Anipryl Information

Generic Name
Selegiline (see-ledge’-a-leen)

Brand Name(s)
Anipryl (Pfizer Animal Health), Eldepryl (GlaxoSmithKline)

What is this medication used for:
There are two uses for L-Deprenyl in the dog: the treatment of Cushing’s disease, an adrenal hormone imbalance, and the treatment of senile mental deterioration. Anipryl is FDA approved for the treatment of Cushing’s disease in dogs caused by a pituitary tumor. It is also used to treat cognitive dysfunction. The usual starting dose for treating Cushing's disease is 0.45 mg/pound given in the morning. If no results within 2 months, may increase to 0.9 mg/pound once a day. If no response within 1 month of the increased dose, reevaluate the patient. The dose for Canine Cognitive Dysfunction is 0.2-0.45 mg/pound. It may take up to one month or more to see improvement

How is Anipryl medication used:
There are two main uses of this medication: the treatment of pituitary dependent Cushing’s disease in the dog and the treatment of canine cognitive dysfunction (senility). In treating Cushing’s disease, Anipryl is given once a day for two months. If no response is seen in this time, the dose is doubled for an additional month. If still no response is seen, another form of treatment should be pursued. Approximately 80% of dogs with Cushing’s disease will respond to L-Deprenyl.

A lower dose of L-deprenyl is used in the treatment of canine cognitive dysfunction. Of the 69 dogs mentioned above, approximately 76% showed improvement on L-deprenyl after one month of therapy. Some dogs improve in the first few days or weeks, some dogs did not show improvement until the second month. Often dogs would continue to improve during the first three months. If no improvement is seen after the first month, the dose is doubled for an additional one month before re-evaluating the patient for an underlying medical problem that could be causing the behavor problems observed.

What are the side effects:
Side effects when using Anipryl may include vomiting, diarrhea, drowsiness, disorientation, hair loss, and shaking.

 

 

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